M6
jfo_jfm_manufacturing-operations-production-supervision-upstream-processing::M6
Senior Director, Manufacturing Operations (Upstream Processing)

Senior Director, Manufacturing Operations (Upstream Processing)

jfo_jfm_manufacturing-operations-production-supervision-upstream-processing · M6 — M6 — Vice President · Management

Senior executive leader accountable for all upstream manufacturing operations across a site or network, setting production strategy and ensuring reliable, compliant supply.

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6 of 8

Track

Management

Family rungs priced

51-0000

Coordinates

3 / 4 spaces

pay@2 · 2026-07

What this role is

Senior executive leader accountable for all upstream manufacturing operations across a site or network, setting production strategy and ensuring reliable, compliant supply. At the Vice President (M6) level, the role owns a major function or division, enterprise priorities and external factors, and drives division-wide / organization-wide. Leads the leadership of a division.

What this level does

  • Lead upstream manufacturing across multiple departments or divisions through senior managers, with decisions carrying long-term effect on company supply capability
  • Define long-term upstream operations strategy for abstract, cross-functional problems spanning network capacity, technology adoption and regulatory posture
  • Negotiate with executives and external partners on critical matters of capacity expansion, technology transfer and supply commitments
  • Influence company manufacturing policy and standards, embedding Lean/Six Sigma and digital-production practices as enterprise capability
  • Own the strategic capital and workforce roadmap that scales upstream production to meet future business growth
Knowledge applied
Defines long-term upstream strategy across departments/divisions, leading through senior managers.
Complexity & problem solving
Tackles abstract, cross-functional problems shaping network capacity and technology direction long-term.
Collaboration & interaction
Negotiates with executives and external partners on critical matters; influences company manufacturing policy.
Typical experience
12–15+ years of deep leadership across departments or divisions.

Skills at this level

Upstream Process Execution
Executes cell-culture/fermentation batch records, work instructions and SOPs with a right-first-time discipline, monitoring each process step to keep runs within specification.
Production Scheduling & Workflow Control
Plans and assigns daily upstream tasks and output goals against the production schedule, and maintains workflow by monitoring process steps and equipment availability.
Mechanical & Equipment Knowledge
Applies knowledge of bioreactor and production equipment design, use, repair and maintenance to keep upstream lines running and to diagnose stoppages.
Lean / Continuous Improvement
Uses lean manufacturing and Six Sigma tools to eliminate waste, reduce deviations and implement cost-reduction measures across the upstream operation.
Statistical Process Control
Analyzes upstream process and yield data with SPC and quality-analysis software such as Minitab to detect drift and control batch quality.
Safety & Regulatory Adherence
Practices and enforces safe work habits and equipment-operation protocols, maintaining compliance with standards such as OSHA on the production floor.
Manufacturing Systems Proficiency
Uses ERP and manufacturing/inventory software (e.g., SAP) to record production, track consumables and order-process against the upstream schedule.
Team Leadership
Coordinates cross-functional teams and skilled operators under tight production schedules with a results-driven mindset, training and directing shift staff.
Cross-Functional Coordination
Collaborates with maintenance, quality control and supply chain to resolve equipment and batch issues and align capacity to the production plan.
Operations Budgeting
Makes budgetary recommendations on capital expenditures and direct/indirect labor for the upstream area and manages variance against the operating plan.
Data-Driven Decision Making
Applies digital production-monitoring tools and yield metrics to prioritize corrective action, set operational strategy and justify capital investment.

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As of · 2026-07-30

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